How Do Liposomes Improve Absorption of CBD?

Science surprise us every day with new discoveries, today I want to share with you important information about a new method that can help improve the way our bodies absorb CBD.

Liposomes are the latest in CBD technology. Phospholipid compounds, liposomes improve the absorption of CBD, transporting it safely through the intestinal membrane and to the tissues that need it.

Sometimes, the greatest advances in the science of cannabis are presented in small formats. This is the case of liposomes, a way to maximize the absorption of CBD in the body with the help of tiny lipid "bubbles".

It seems that CBD is finding its place in science after decades of cannabis prohibition and oppressive stigmatization against cannabinoid drugs. Now that there is a greater awareness of the health benefits of cannabinoids, we are finally approaching an appeasement of tensions in this regard.

As a result, manufacturers are developing more advanced cannabis products to meet the growing demand. Some companies lead the market with their powerful CBD supplements, and increasingly use liposomes to optimize the absorption of this active ingredient.


Liposomes are vesicles composed of one or more phospholipid bilayers. Normally, liposomes are prepared in the laboratory by disrupting the phospholipids to form a spherical protective bubble. Some believe that liposomes are the future of the nutraceutical industry because they administer the active ingredients, safely and through the gastrointestinal tract in the areas where they are needed.

Phospholipids contain a hydrophilic head (affinity to water) and a hydrophobic tail (which repels water). When they submerge in water, the tails fold back on themselves and the heads come out attracted by the water. This causes them to form a bilayer that safely encapsulates the ingredients and protects them from any damage.


Discovered for the first time by Alec D. Bangham and R.W. Horne in 1961, liposomes became important to become the subject of a scientific study published in 1965. Liposomes are the mechanism most used by the pharmaceutical industry for the selective delivery of drugs. Recently, the nutraceutical industry has begun to use liposomes as a mode of transport to increase the bioavailability of nutrients.


One of the main reasons for the generalization of liposomes is their safety. Once again, liposomes are composed of phospholipids and, therefore, are not toxic or immunogenic, but they are biodegradable and biocompatible. Liposomes, and their consumption in medicines and supplements, have virtually no adverse side effects.

Liposomes are a unique method of administration, transporting the ingredients through the intestinal membrane to specific tissues. If they are prepared correctly, they also guarantee total protection for their content. This is the reason why the bioavailability of nutrients is so high when liposomes are used in dietary supplements.


CBD and liposomes are a winning combination in every way. Effective by itself, CBD is being studied as a possible treatment for physical and psychological disorders such as chronic pain, post-traumatic stress disorder, Dravet syndrome and many others. When encapsulated in liposomes, CBD has the ability to deliver its beneficial properties to the tissues that need it. By protecting CBD, liposomes improve their absorption.

CBD is a non-psychoactive compound, so the ingestion of its complete form is not overwhelming for the consumer. On the other hand, by maximizing the intake of CBD, its positive effects are enhanced. This is true in the case of both oral and topical formulas - two methods of liposomal delivery that are becoming very popular. When used in creams and ointments, liposomes allow the CBD to penetrate deeper into the epidermis to clean the skin thoroughly. When ingested in a supplement, CBD and liposomes provide an accurate and stable dosage.

For those who wish to consume cannabinoids for medicinal purposes, liposomes allow a greater concentration of CBD than in the past. CBD has anxiolytic and anti-inflammatory properties, and is a potent regulator of the psychoactive cannabinoid THC and other natural ingredients.


A 2017 study found that delivery systems based on "nanoparticles", such as liposomes, improve the bioavailability of nutrients by protecting the drug in the gastrointestinal tract and the mucous membrane, in addition to increasing cell contact. The authors confirm the added potential of liposomes thanks to their phospholipid bilayer structure. This unique method allows them to "adhere to biomembranes and form mixed micelles with bile salts to increase the solubility of poorly soluble drugs ..."

Regarding the efficacy of CBD when administered in high percentages, the following 2003 study on "Cannabidiol - transdermal route and anti-inflammatory effect in a murine model" must be taken into account. In this case, a group of blind mice were administered CBD in order to determine their efficacy in the treatment of rheumatic diseases. In response to problems associated with oral intake, the researchers used a method of administering CBD using ethosomes. Throughout the 72 hours that the experiment lasted, the mice were analyzed to determine the variation of the level of CBD in the skin.

In the study it was observed that, not only did a "significant accumulation" of CBD occur in the skin and in the muscles, but there was also a significant reduction in inflammation. In conclusion, the authors point out the possibility of using CBD as an anti-inflammatory treatment when administered by means of safe vehicles such as ethosomes. Although the etosomes and the liposomes are not exactly the same, both have a very similar penetration potential in the organism.


CBD Marketing Spot shall not be held liable for the medical claims made by customer testimonials. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products and the testimonials made have not been confirmed by FDA- approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your healthcare professional about potential interactions or other possible complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.


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